Current Issue : January - March Volume : 2016 Issue Number : 1 Articles : 7 Articles
Background. To evaluate the potential diagnostic value of CDI of retrobulbar hemodynamic changes in NTG patients. Methods.\nRelevant publications which included PSV, EDV, and RI of OA, CRA, NPCA, and TPCA in NTG patients and normal controls\nmeasured by CDI were retrieved from the Cochrane Central Register of Controlled Trials, PubMed, the ISI Web of Knowledge,\nand EMBASE from 1990 to 2014. Subgroup analyses were made based on IOP-lowering medications uses. Result. In OA, there was\nsignificant decrease of PSV with moderate heterogeneity (...
Purpose: To identify the clinical features of the syndrome Frank-Kamenetsky and determine the\ncriteria of early formation of glaucoma. Materials and Methods: We observed 52 patients. Follow\nup period was from 5 to 22 years. The first group (juvenile) consisted of males who had the first\nsigns of glaucoma diagnosed before the age of 12 (n = 22). The average age of the group was 10.1 �±\n2.4 years. The control group included healthy males (n = 30) in the same age range (average age\n7.2 �± 1.6 years). The second group (adults) consisted of patients who had the first signs of glaucoma\ndiagnosed after the age of 18 and elder. The average age of the group was 32.44 �± 6.28 years.\nThe control group had males (n = 30) in the same age range (average age 26.59 �± 4.12 years). The\ninclusion criterion was: the presence of congenital bilateral mesodermal iris leaf hypoplasia, trabecular\ndysgenesis signs, the presence of blood relatives on the maternal line (grandfather, uncle)\nmale with similar changes iridociliary zone and glaucoma. Criteria of glaucoma formation were:\nincreased IOP more than 21 mmHg with accompanying it expansion of the cup/disc ratio, reducing\nthe thickness of the nerve fiber layer (RNFL) according to OCT. Results: It was found that Frank-\nKamenetsky Syndrome had an X-linked with sex, recessive inheritance and was characterized by\nbilateral congenital irisdysgenesis and goniodysgenesis with the accession glaucoma. Predictors\nof glaucoma formation in early childhood are a combination of: 1) congenital subtotal atrophy of\niris mesodermal layer (from 0 to 30 mkm) with signs of progressive dystrophy; 2) nonprogressive\ncongenital megalocornea (cornea diameter 12 - 14 mm); 3) iridotrabecular dysgenesis of II-III degree;\n4) hyperopic refraction in axial myopia....
The effects of lutein and zeaxanthin on lipopolysaccharide- (LPS-) induced secretion of IL-8 by uveal melanocytes (UM) were tested\nin cultured human UM.MTT assay revealed that LPS (0.01ââ?¬â??1 ...
Purpose. To evaluate the variations in macular thickness in young Chinese myopic persons and the association with axial length\n(AL), spherical equivalence refraction (SE), age, intraocular pressure, and sex. Methods. In total, 133 young Chinese myopic\nsubjects between 18 and 30 years of age were selected. The macular thickness was assessed using third-generation optical coherence\ntomography. AL, intraocular pressure, and SE were also measured. Results. The mean central foveal thickness was 191.1 �± 15.3 ...
Retinitis pigmentosa is a clinical and genetic group of inherited retinal disorders characterized by alterations of photoreceptors and\nretinal pigment epithelium leading to a progressive concentric visual field restriction, which may bring about severe central vision\nimpairment. Haemodynamic studies in patients with retinitis pigmentosa have demonstrated ocular blood flow abnormalities\nboth in retina-choroidal and in retroocular vascular system. Moreover, several investigations have studied the augmentation of\nendothelin-1 plasma levels systemically in the body and locally in the eye. This might account for vasoconstriction and ischemia,\ntypical in vascular dysregulation syndrome, which can be considered an important factor of reduction of the ocular blood flow in\nsubjects affected by retinitis pigmentosa....
Purpose. To evaluate the safety and efficacy of intracameral vancomycin during cataract surgery using a standardized dosage\nand delivery technique. Methods.The charts of 20,719 consecutive eyes that underwent phacoemulsification with intraocular lens\nimplantation in a single ambulatory surgery center were retrospectively reviewed over a 5-year period. Results. The first 11,333\nconsecutive cases did not receive intracameral vancomycin, whereas the next 9,386 consecutive cases all received intracameral\nvancomycin. There were no significant differences in the baseline characteristics between the cohort of subjects who received\nintracameral vancomycin and the cohort of subjects that did not. There were a total of 11 subjects (0.97 cases per 1,000) that\ndeveloped postoperative endophthalmitis in the group that did not receive intracameral vancomycin, whereas there were no cases\nof postoperative endophthalmitis in the group that received intracameral vancomycin (p = 0.0015).The overall rate of intraoperative\nand postoperative complications and the final postoperative visual acuities were similar among cohorts. There were no cases of toxic\nanterior segment syndrome occurring in either group during the study period. Conclusions. Routine administration of intracameral\nvancomycin during cataract surgery significantly decreased the incidence of postoperative endophthalmitis and was not associated\nwith an increased incidence of postoperative adverse events....
Purpose. To evaluate longitudinal functional and anatomical results after combined pars plana vitrectomy (PPV) and penetrating\nkeratoplasty (PKP) using a wide-field Landers intraoperative temporary keratoprosthesis (TKP) in patients with vitreoretinal\npathology and corneal opacity due to severe ocular trauma. Material and Methods. Medical records of 12 patients who had\nundergone PPV/PKP/KP due to severe eye trauma were analyzed. Functional (best-corrected visual acuity) and anatomic outcomes\n(clarity of the corneal graft, retinal attachment, and intraocular pressure) were assessed during the follow-up (mean 16 months).\nResults. Final visual acuities varied from NLP to CF to 2m.Visual acuity improved in 7 cases, was unchanged in 4 eyes, and worsened\nin 1 eye.The corneal graft was transparent during the follow-up in 3 cases and graft failure was observed in 9 eyes. Silicone oil was\nused as a tamponade in all cases and retina was reattached in 92% of cases. Conclusions. Combined PPV and PKP with the use of\nwide-field Landers TKP allowed for surgical intervention in patients with vitreoretinal pathology coexisting with corneal wound.\nAlthough retina was attached in most of the cases, corneal graft survived only in one-fourth of patients and final visual acuities\nwere poor....
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